沈莉菁：上海仁济医院血液科副主任医师

　　沈莉菁，医学博士副主任医师 主要从事血液系统恶性疾病的诊断及规范化治疗，结合每年的国际指南和本科室诊治经验积累，在白血病危险度分层和个体化治疗方面进行了大量创新实践，显著提高了患者的缓解期和生活质量。熟练掌握淋巴瘤、骨髓瘤的规范化免疫化疗和新型靶向药物等综合治疗措施的运用。对红细胞和血小板异常的诊治积累了较为丰富的临床经验，参与规范化临床路径修订和实施，降低了整体医疗费用。硕士生导师；上海市医学会血液学专业委员会青年学组委员；上海中西医结合学会血液分会青年委员近五年发表文章，1.Shen LJ, Zhu JY, Chen FY, Lin WJ, Jiayi Cai, Zhong JH, Zhong H. RUNX1-Evi-1 fusion gene inhibited differentiation and apoptosis in myelopoiesis: an in vivo study. BMC Cancer. 2015 Dec(16)15:970. 2.Zhou LY, Chen FY, Shen LJ, Wan HX, Zhong JH. Arsenic trioxide induces apoptosis in the THP1 cell line by downregulating EVI-1. Exp Ther Med. 2014 Jul;8(1):85-90. 3.Shen LJ, Chen FY, Zhang Y, Cao LF, Kuang Y, Zhong M. MYCN transgenic zebrafish model with the characterization of acute myeloid leukemia and altered hematopoiesis. PLoS One. 2013. 8(3): e59070.4.Shen LJ, Cao LF, Chen FY, Zhang Y, Zhong JH, Zhong H. Using modified whole-mount hybridization to study expression in zebrafish. Exp Ther Med. 2013. 5(4): 1043-1047.5.Tang CH, Shen LJ, Gao Q, Yang Y, Chen LX. Hyperfibrinolysis after parapelvic cyst surgery: A case report. Exp Ther Med. 2013. 5(1): 271-276.6.Shen LJ, Cao LF, Chen FY. [Research progress of N-myc roles in hematopoiesis and hematologic malignancies]. Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2013. 21(2): 503-7.7.H-H Huang, J-Y Zhu, J-Y Han, L-J Shen, Xu, X-L, Chen, F-Y* Chen*. Co-existent de novo Myelodysplastic Syndrome and T-cell Non-Hodkim lymphoma: a Common origin or Not? J of Inter. Medical Reserch. 2009. 37(1): 270-276.8.Shen LJ, Chen FY, Wang T, et al. [Polymorphisms of CYP3A5 gene in acute leukemia patients and their role in chemotherapy and prognosis]. Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2008. 16(1): 26-30.9.沈莉菁,陈芳源,钟济华,王婷,王海嵘,徐岚,韩洁英,钟华,欧阳仁荣.遗传因素对白血病CYP3A5耐药机制的影响[J].肿瘤,2009,03:259-264.10.沈莉菁,韩洁英,陈芳源.原发性嗜酸粒细胞增多症的诊疗进展[J].临床血液学杂志,2008,03:285-288.11.沈莉菁,陈芳源,肖菲,韩洁英,钟华,钟璐,黄洪晖,徐岚. 伏立康唑治疗血液病合并侵袭性真菌感染23例[J]. 中国感染与化疗杂志,2010,(03):216-219.12.沈莉菁,韩洁英,陈芳源,黄洪晖,钟华,徐岚,欧阳仁荣. 急性早幼粒细胞白血病疗效随访(附78例报告)[J]. 上海医学,2007,(01):37-39.13.沈莉菁,陈芳源,韩洁英,黄洪晖,钟华,钟璐,胡霄飞,欧阳仁荣. CAG方案治疗初治急性髓系白血病的疗效观察[J]. 临床血液学杂志,2004,(06):355-357.近三年国际学术会议交流:1.Li-Jing SHEN， Fang-Yuan CHEN*， Wen-Jie Lin， Ji-Hua Zhong. The influence of AML1-EVI1 gene on the transcriptional regulation of hematopoiesis，1st Zebrafish for Personalized/Precision Medicine Conference，Poster-1603.2.Li-Jing SHEN， Fang-Yuan CHEN*， Ji-Hua Zhong. Shikonin Derivative Inhibits Angiogenesis in Zebrafish，2013，18th World Congress on Advances in Oncology，Poster-430.3.Li-Jing Shen， Fang-Yuan Chen*， Zheng-Hua Xuan. Altered genes downstream of MYCN in acute myeloid leukemia in zebrafish by retinoic acid and valproic acid，2013，18th EHA，Poster-643. 4.Li-Jing Shen， Fang-Yuan Chen， Yong Zhang， Lan-Fang Cao and Hua Zhong. Functional Enrichment An-alysis by DAVID in Transgenic MYCN Zebrafish Model. Blood. 2012，54th ASH，Abstract.5.SHEN Li-Jing， CHEN Fang-Yuan*， LIN Wen-Jie， KUANG Ying， INHIBITING ANGIOGENESIS ACTIVITIES OF QUERCETIN HYDRATE IN ZEBRAFISH. 2012，17th EHA，Poster-476.6.CHEN Fang-Yuan， SHEN Li-Jing， ZHANG Yong， KUANG Ying. The influence of Hematopoietic Regulatory Factors by Evi-1 Transgenic Model in the Zebrafish. Blood. 2011，53th ASH，Abstract.7.SHEN Li-Jing， CHEN Fang-Yuan*， ZHONG Min， ZHANG Yong， KUANG Ying， ZHONG Hua， ZHONG Ji-Hua. The influence of MYCN gene on the transcriptional regulation of hematopoiesis. 2011，16th EHA，Poster-751.多次获得上海市血研所“先进员工”和医院“三八红旗手”、“优秀共产党员”、“比翼双飞模范佳侣”称号，以及院“教学工作先进个人”和“骨干教师”称号。1998年，毕业于上海第二医科大学，获学士学位；2007年，上海交通大学医学院，获医学硕士学位；2013年，上海交通大学医学院，获医学博士学位；2014~2015年，美国Fox Chase 癌症中心访学；2015年10月，加拿大渥太华医学院学习交流；