张彦：大连医科大学附属第二医院免疫风湿科主任医师

　　在研项目：IL-34促进类风湿关节炎滑膜细胞表达OX40L上调Tfh的机制研究代表文章：1.Increased IL-6 expression on THP-1 by IL-34 stimulation up-regulated rheumatoid arthritis Th17 cells. Clin Rheumatol. 2018 Jan;37(1):127-137. Wang B1, Tang Y1, Sun X1, Ouyang X1, Li H1, Wei J1, Zhang Y2, Li X3. IF:3.41 通讯作者 2.Rheumatoid arthritis fibroblast-like synoviocytes co-cultured withPBMC increased peripheral CD41CXCR51ICOS1 T cell numbers. Clinical and Experimental Immunology . 2017Tang,*1 B. Wang,*1 X. Sun,*H. Li,* X. Ouyang,* J. Wei,* B. Dai,?Y. Zhang? and X. Li IF:2.365 通讯作者 3.IL-34 modulates rheumatoid synovial fibroblasts proliferation and migration via ERK/AKT signalling pathway. Clinical and Experimental Rheumatology. 2019 IF: 3.238通讯作者 4.IL-34 modulates rheumatoid synovial fibroblast proliferation and migration via ERK/AKT signalling pathway. Clinical and Experimental Rheumatology 2019 IF:3.319 5.Indian Hedgehog regulates senescence in bone marrow-derived mesenchymal stem cell through modulation of ROS/mTOR/4EBP1, p70S6K1/2 pathway IF:4.831

　　擅长：类风湿关节炎、系统性红斑狼疮、强直性脊柱炎、干燥综合征、系统性血管炎、强直性脊柱炎、痛风、干燥综合征、皮肌炎、硬皮病等常见病以及风湿病疑难、重症疾病的诊治。